Coordonnées de l'entreprise

    Date : Parue le 11/04/2025 Fonction : Recherche & Analyses Localisation Ile-de-France - Paris - 13ème arrondissement (75013) Contrat CDI Experience 1-2 ans

    Votre mission :

    CONTEXT:

    The Paris Brain Institute’s electrophysiology core facility (ePHYS) provides services to researchers for functional investigation of neural processes underlying brain activity. The facility offers in vitro, ex vivo and in vivo electrophysiology services applied to a variety of preclinical models ranging from 3D hIPSC cultures and brain slices to behaving animals. Our team provides specialized training, scientific technical support and data generation for advanced research projects. The core facility is embedded in a highly dynamic and collaborative environment involving more than 20 research teams. 

     ePHYS is recruiting a Research Engineer in in vivo electrophysiology.

    JOB DESCRIPTION:

     The Research Engineer will lead projects requiring in vivo electrophysiology technologies. This position is ideal for an individual interested in data acquisition and analysis using intracerebral neurophysiology.

     The research projects will include EEG/ECoG recordings combined with video monitoring and possibly imaging methods (e.g. fiber photometry). 

    The Research Engineer will also be responsible for implementing new technologies, such as high-density recordings of neural activity. The position will also involve the analysis of data sets, with support from computational neuroscientists on site. 



    MAIN RESPONSIBILITIES:

    - Design experimental protocols and establish procedures for in vivo electrophysiological studies, including models of experimental epilepsy
    - Implement and optimize surgical and data acquisition procedures
    - Conduct research using combined video monitoring and EEG/ECoG recordings to monitor brain activity in freely behaving rodents
    - Develop systems, processes, and procedures for data management
    - Perform statistical and qualitative data analysis
    - Report research findings to client research team
    - Provide training and support to users, including for surgery, data collection and analysis
    - Develop new assays and electrophysiological approaches using multi-channel silicon probes

    Votre profil :

    PROFILE

    - Ph.D. in neuroscience or related fields such as engineering and computational biology
    - At least 2 years of experience in in vivo electrophysiology 
    - Personal license to perform animal experiments, including stereotaxic surgery in rodents

     
    Know-How

    - Expertise and strong interest in neuroscience data analysis methods   
    - Programming experience in languages such as Python, R, MATLAB
    Solid record of international peer-reviewed publications


    Soft skills

    - Ability to manage multiple projects simultaneously
    - Ability to work effectively with multi-disciplinary and international research teams
    - Excellent communication and writing skills
    - Fluency in English (French is not required)


    The Brain Institute is committed to combating all forms of discrimination. We guarantee an inclusive and respectful working environment for all diversities. 
    All our positions are open to individuals with disabilities.

    APPLICATION:

     Please send your CV, a cover letter, and professional references to:  

    ephys[a]icm-institute.org and the Paris Brain Institute’s career page

    https://offres.institutducerveau-icm.org//fr/jobs/1879-26

     
    Informal inquiries are welcome, please contact us for more information.

    A propos de INSTITUT DU CERVEAU :

    L'Institut du Cerveau est un établissement dédié à la recherche, à la compréhension et au traitement des troubles neurologiques et des maladies du cerveau. L'Institut unit des scientifiques de diverses disciplines, notamment la neurologie, la neurochirurgie, la neuro-imagerie, la neuropsychologie et la génétique, dans le but de collaborer sur des projets de recherche novateurs.
    Les objectifs incluent la découverte de nouvelles thérapies pour traiter les maladies neurologiques telles que la maladie d'Alzheimer, la maladie de Parkinson, la sclérose en plaques, les troubles du mouvement, les troubles de l'humeur et bien d'autres. Ils cherchent également à mieux comprendre le fonctionnement du cerveau humain dans des états normaux et pathologiques.